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Biotechnology Manufacturing, 6 credits
Bioteknisk tillverkningsteknik, 6 hp
TFTB39
Main field of study
Engineering BiologyCourse level
Second cycleCourse type
Programme courseExaminer
Carl-Fredrik MandeniusDirector of studies or equivalent
Magnus BomanEducation components
Preliminary scheduled hours: 66 hRecommended self-study hours: 94 h
ECV = Elective / Compulsory / Voluntary
| Course offered for | Semester | Period | Timetable module | Language | Campus | ECV | |
|---|---|---|---|---|---|---|---|
| 6CKEB | Chemical Biology (Industrial Biotechnology and Production) | 8 (Spring 2017) | 2 | 3+4 | Swedish | Linköping, Valla | C |
| 6CTBI | Engineering Biology, M Sc in Engineering (Industrial Biotechnology and Production) | 8 (Spring 2017) | 2 | 3+4 | Swedish | Linköping, Valla | C |
Main field of study
Engineering BiologyCourse level
Second cycleAdvancement level
A1XCourse offered for
- Chemical Biology
- Engineering Biology, M Sc in Engineering
Entry requirements
Note: Admission requirements for non-programme students usually also include admission requirements for the programme and threshold requirements for progression within the programme, or corresponding.
Prerequisites
Courses in technology and natural sciences according to the KB/TB program year 1-3. Ability to simulate bioreactors using MATLAB or equivalent software programs. Basic knowledge on large-scale bioprocessing. Basic knowledge on production systems in industrial biotechnology, biostatistics, and pharmaceuticals based on biotechnology.
Intended learning outcomes
The course gives the students an overview of the field and give them experience in solving engineering tasks of process analytical and process design character. Focus is on manufacturing of biologicals. Practical training in cultivation techniques and use of bioreactor equipment. Training in oral and written reporting using adequate engineering terminology. Good understanding for principles of process analytical technology concepts (PAT) and quality by design (QbD) aspects on manufacturing.
Course content
Design and simulation methodology for industrial biotechnical production processes. Focus on pharmaceutical products. Training in culturing protein producing organisms and use of advanced monitoring and control techniques; design tool software programming; mathematical modelling of key design issues. Analytical methods for cultivation and in-process control. Regulatory quality guidelines for biotechnology manufacturing. Training in presentation skills.
Teaching and working methods
The course program is based on classes, laboratory modelling and project. The project takes three full days. The course is coordinated with the CDIO-course TFTB32 and NKED20 Pharmaceutical Development.
Examination
| LAB1 | Written laboratory report | 2 credits | U, G |
| UPG1 | Project | 4 credits | U, 3, 4, 5 |
| UPPG1 | 0 credits |
Participation at seminars (80%).
Project report is graded
Project report is graded
Grades
Four-grade scale, LiU, U, 3, 4, 5Department
Institutionen för fysik, kemi och biologiDirector of Studies or equivalent
Magnus BomanExaminer
Carl-Fredrik MandeniusEducation components
Preliminary scheduled hours: 66 hRecommended self-study hours: 94 h
Course literature
Mandenius CF, Föreläsnings- och laborationskompendium, Tryckakademin, Linköping| Code | Name | Scope | Grading scale |
|---|---|---|---|
| LAB1 | Written laboratory report | 2 credits | U, G |
| UPG1 | Project | 4 credits | U, 3, 4, 5 |
| UPPG1 | 0 credits |
Participation at seminars (80%).
Project report is graded
Project report is graded
Regulations (apply to LiU in its entirety)
The university is a government agency whose operations are regulated by legislation and ordinances, which include the Higher Education Act and the Higher Education Ordinance. In addition to legislation and ordinances, operations are subject to several policy documents. The Linköping University rule book collects currently valid decisions of a regulatory nature taken by the university board, the vice-chancellor and faculty/department boards.
LiU’s rule book for education at first-cycle and second-cycle levels is available at http://styrdokument.liu.se/Regelsamling/Innehall/Utbildning_pa_grund-_och_avancerad_niva.
Course literature is preliminary.
Mandenius CF, Föreläsnings- och laborationskompendium, Tryckakademin, Linköping
Note: The course matrix might contain more information in Swedish.
I = Introduce, U = Teach, A = Utilize
| I | U | A | Modules | Comment | ||
|---|---|---|---|---|---|---|
| 1. DISCIPLINARY KNOWLEDGE AND REASONING | ||||||
| 1.1 Knowledge of underlying mathematics and science (G1X level) |
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X
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| 1.2 Fundamental engineering knowledge (G1X level) |
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X
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| 1.3 Further knowledge, methods, and tools in one or several subjects in engineering or natural science (G2X level) |
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X
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| 1.4 Advanced knowledge, methods, and tools in one or several subjects in engineering or natural sciences (A1X level) |
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| 1.5 Insight into current research and development work |
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| 2. PERSONAL AND PROFESSIONAL SKILLS AND ATTRIBUTES | ||||||
| 2.1 Analytical reasoning and problem solving |
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X
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| 2.2 Experimentation, investigation, and knowledge discovery |
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X
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| 2.3 System thinking |
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X
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| 2.4 Attitudes, thought, and learning |
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X
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| 2.5 Ethics, equity, and other responsibilities |
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X
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| 3. INTERPERSONAL SKILLS: TEAMWORK AND COMMUNICATION | ||||||
| 3.1 Teamwork |
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X
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| 3.2 Communications |
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X
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| 3.3 Communication in foreign languages |
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X
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| 4. CONCEIVING, DESIGNING, IMPLEMENTING AND OPERATING SYSTEMS IN THE ENTERPRISE, SOCIETAL AND ENVIRONMENTAL CONTEXT | ||||||
| 4.1 External, societal, and environmental context |
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X
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| 4.2 Enterprise and business context |
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X
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| 4.3 Conceiving, system engineering and management |
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X
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| 4.4 Designing |
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X
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| 4.5 Implementing |
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X
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| 4.6 Operating |
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X
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| 5. PLANNING, EXECUTION AND PRESENTATION OF RESEARCH DEVELOPMENT PROJECTS WITH RESPECT TO SCIENTIFIC AND SOCIETAL NEEDS AND REQUIREMENTS | ||||||
| 5.1 Societal conditions, including economic, social, and ecological aspects of sustainable development for knowledge development |
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X
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| 5.2 Economic conditions for knowledge development |
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X
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| 5.3 Identification of needs, structuring and planning of research or development projects |
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X
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| 5.4 Execution of research or development projects |
X
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| 5.5 Presentation and evaluation of research or development projects |
|
X
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