Project course: Drug Development, 6.0 credits

Main field of study

Course level

Advancement level

Course offered for

• Experimental and Industrial Biomedicine
• Bachelor´s Programme in Experimental and Industrial Biomedicine

Entry requirements

General entry requirements for undergraduate studies
and
Chemistry, Mathematics and Biology corresponding to the level in Swedish upper secondary education (Chemistry 2, Mathematic 4 and Biology 2)
and
English corresponding to the level of English in Swedish upper secondary education (English 6)

Exemption from Swedish 3

Intended learning outcomes

Knowledge and understanding

Having completed the course, the student is expected to be able to:

• Describe the principles of how low molecular weight substances that increase or decrease the activity of target molecules (agonists/antagonists) can be identified through screening
• Describe the principles of in vitro high-throughput screening and cell-based screening 
• Demonstrate a basic understanding of desirable properties in small molecules for further development
• Describe the principles of protein production in prokaryote and eukaryote systems for further therapeutic use

Skills and abilities

On completion of the course, the student shall be able to:

• Apply laboratory methods of drug screening
• Critically appraise the principles of assay development (sensitivity and specificity)
• Compile, analyse and present results orally and in writing

Judgement ability and approach

On completion of the course, the student shall be able to:

• Critically appraise and evaluate knowledge within the field of drug development from an academic, ethical and social perspective.

Course content

The course is a basic course in drug development. It includes practical elements in which collections of small molecules are screened to determine pharmacological properties on cell activity. Manufacturing of recombinant proteins is used to illustrate the principles of the production of protein drugs. The course also aims to create an understanding of the principles of lead optimisation within drug development.

Teaching and working methods

At the Faculty of Medicine and Health Sciences student centred and problem based learning make up the foundation of the teaching. The student takes responsibility for, studies and researches current content of the courses and study programme. The methods of the course work challenge the students to independently formulate questions for learning, to seek knowledge and in dialogue with others judge and evaluate achieved knowledge. Students in the Bachelor’s programme in Experimental and Industrial Biomedicine work together in groups based on reality based and course related biomedical issues to apply their knowledges, develop their own learning, contribute to the fellow students’ learning and to practice cooperation. Throughout the study programme theory is integrated with practical modules. The course methods and integration modules stimulates and support the student’s ability to apply their knowledge and professional competence.

Working methods used in this course are lectures, seminars, laboratory sessions and work in project groups.

Examination

The form of examination is an written project report and an oral presentation carried out in groups but assessed individually. In addition, active and approved participation in compulsory course elements is required in order to pass the course. Compulsory course elements include project work, seminars, reports and written assignments.

The written project report and the oral presentation are resource-demanding forms of examination and are limited to five attempts 

If special circumstances prevail, and if it is possible with consideration of the nature of the compulsory component, the examiner may decide to replace the compulsory component with another equivalent component.

Application for examination

Instructions on how to apply for examinations are given prior to the beginning of each course.

Re-examination

The date for re-examination should normally be announced by the date of the regular examination at latest; in which case the scope must be the same as at the regular examination.

Examination for students with disabilities

If the LiU coordinator for students with disabilities has granted a student the right to an adapted examination for a written examination in an examination hall, the student has the right to it.

If the coordinator has recommended for the student an adapted examination or alternative form of examination, the examiner may grant this if the examiner assesses that it is possible, based on consideration of the course objectives. 

An examiner may also decide that an adapted examination or alternative form of examination if the examiner assessed that special circumstances prevail, and the examiner assesses that it is possible while maintaining the objectives of the course. 

Nomination of another examiner

A student who has taken two examinations in a course or a part of a course without obtaining a pass grade is entitled to the nomination of another examiner, unless there are special reasons to the contrary.  

Grades

Course literature

A literature reference list must be set no later than two months before the course begins by the programme committee for the Bachelor’s Programme in Experimental and Industrial Biomedicine. There is no compulsory course literature. 

Other information

Planning and implementation of the course is to be based on the wordings in the course syllabus. A course evaluation is compulsory for each course and should include how the course is in agreement with the course syllabus. The course coordinator will analyse the course evaluation and propose appropriate development of the course. The analysis and proposal will be returned to the students, the Director of Studies, and as needed to the Education Board, if related to general development and improvement.

The course is carried out in such a way that knowledge of gender, gender identity/expression, ethnicity, religion or other belief system, disability, sexual orientation and age is addressed, highlighted and communicated as part of the programme.

If the course is cancelled or undergoes major changes, examination is normally offered under this course syllabus, at a total of three occasions, within/in connection to the two following semesters, of which one in close proximity to the first examination.

Department