Drug Discovery and Pharmaceutical Development, 6 credits

Läkemedelsutveckling, 6 hp

NKED20

Course starting semester

Main field of study

Engineering Biology Chemical Biology

Course level

Second cycle

Course type

Programme course

Examiner

Peter Nilsson

Director of studies or equivalent

Magdalena Svensson

Education components

Preliminary scheduled hours: 48 h
Recommended self-study hours: 112 h

Available for exchange students

Yes

Possible deviation from course syllabus/programme syllabus

ECV = Elective / Compulsory / Voluntary

Course offered for		Semester	Period	Timetable module	Language	Campus	ECV
6CKEB	Chemical Biology (Industrial Biotechnology and Production)	8 (Spring 2017)	2	2	English	Linköping, Valla	C
6CKEB	Chemical Biology (Protein Science and Technology)	8 (Spring 2017)	2	2	English	Linköping, Valla	C/E
6CTBI	Engineering Biology, M Sc in Engineering (Industrial Biotechnology and Production)	8 (Spring 2017)	2	2	English	Linköping, Valla	C
6MKOS	Organic Synthesis and Medicinal Chemistry, Master's programme	2 (Spring 2017)	2	2	English	Linköping, Valla	C
6MPRO	Protein Science, Master's programme (External)	2 (Spring 2017)	2	2	English	Linköping, Valla	E
6MPRO	Protein Science, Master's programme (Internal)	2 (Spring 2017)	2	2	English	Linköping, Valla	E

Main field of study

Engineering Biology, Chemical Biology

Course level

Second cycle

Advancement level

A1X

Course offered for

Chemical Biology
Engineering Biology, M Sc in Engineering
Organic Synthesis and Medicinal Chemistry, Master's programme
Protein Science, Master's programme

Entry requirements

Note: Admission requirements for non-programme students usually also include admission requirements for the programme and threshold requirements for progression within the programme, or corresponding.

Prerequisites

Medicinal Chemistry, Organic Synthesis, Protein Chemistry, Advanced Organic Synthesis.

Intended learning outcomes

After completing the course, the student should be able to:

synthesis of aromatic heterocycles
explain drug discovery, design and development
account for antibacterial agents
account for antiviral agents
account for anticancer agents
account for drugs acting on the nervous system

Course content

The course will give advanced knowledge of the drug discovery, design and development in different research areas like infectious diseases, anticancer agents and drugs acting on the nervous system. The course also includes synthesis and process development of drugs.

Teaching and working methods

The education includes lectures, seminars and laboratory work.

Examination

UPG1	Group assignments including written and oral presentations	1.5 credits	U, G
LAB1	Laboratory work	0.5 credits	U, G
TEN1	Written examination	4 credits	U, 3, 4, 5

To pass the laboration course practical performance and approved reports is required

Grades

Four-grade scale, LiU, U, 3, 4, 5

Department

Institutionen för fysik, kemi och biologi

Director of Studies or equivalent

Magdalena Svensson

Examiner

Peter Nilsson

Education components

Preliminary scheduled hours: 48 h
Recommended self-study hours: 112 h

Course literature

Graham L. Patrick: An Introduction to Medicinal Chemistry, A. Claesson, B. Danielsson och U. Svensson: Läkemedelskemi. Publikationer från läkemedelskemiska tidskrifter.

Code	Name	Scope	Grading scale
UPG1	Group assignments including written and oral presentations	1.5 credits	U, G
LAB1	Laboratory work	0.5 credits	U, G
TEN1	Written examination	4 credits	U, 3, 4, 5

To pass the laboration course practical performance and approved reports is required

Regulations (apply to LiU in its entirety)

The university is a government agency whose operations are regulated by legislation and ordinances, which include the Higher Education Act and the Higher Education Ordinance. In addition to legislation and ordinances, operations are subject to several policy documents. The Linköping University rule book collects currently valid decisions of a regulatory nature taken by the university board, the vice-chancellor and faculty/department boards.

LiU’s rule book for education at first-cycle and second-cycle levels is available at http://styrdokument.liu.se/Regelsamling/Innehall/Utbildning_pa_grund-_och_avancerad_niva.

Student rights and obligations (login required)
Linköping University common rules and regulations (in Swedish)

Course literature is preliminary.

Graham L. Patrick: An Introduction to Medicinal Chemistry, A. Claesson, B. Danielsson och U. Svensson: Läkemedelskemi. Publikationer från läkemedelskemiska tidskrifter.

Download

Download course literature list as PDF

Note: The course matrix might contain more information in Swedish.

I = Introduce, U = Teach, A = Utilize

		I	U	A	Modules	Comment
1. DISCIPLINARY KNOWLEDGE AND REASONING
	1.1 Knowledge of underlying mathematics and science (G1X level)
	1.2 Fundamental engineering knowledge (G1X level)
	1.3 Further knowledge, methods, and tools in one or several subjects in engineering or natural science (G2X level)
	1.4 Advanced knowledge, methods, and tools in one or several subjects in engineering or natural sciences (A1X level)
	1.5 Insight into current research and development work
2. PERSONAL AND PROFESSIONAL SKILLS AND ATTRIBUTES
	2.1 Analytical reasoning and problem solving
	2.2 Experimentation, investigation, and knowledge discovery
	2.3 System thinking
	2.4 Attitudes, thought, and learning
	2.5 Ethics, equity, and other responsibilities
3. INTERPERSONAL SKILLS: TEAMWORK AND COMMUNICATION
	3.1 Teamwork
	3.2 Communications
	3.3 Communication in foreign languages
4. CONCEIVING, DESIGNING, IMPLEMENTING AND OPERATING SYSTEMS IN THE ENTERPRISE, SOCIETAL AND ENVIRONMENTAL CONTEXT
	4.1 External, societal, and environmental context
	4.2 Enterprise and business context
	4.3 Conceiving, system engineering and management
	4.4 Designing
	4.5 Implementing
	4.6 Operating
5. PLANNING, EXECUTION AND PRESENTATION OF RESEARCH DEVELOPMENT PROJECTS WITH RESPECT TO SCIENTIFIC AND SOCIETAL NEEDS AND REQUIREMENTS
	5.1 Societal conditions, including economic, social, and ecological aspects of sustainable development for knowledge development
	5.2 Economic conditions for knowledge development
	5.3 Identification of needs, structuring and planning of research or development projects
	5.4 Execution of research or development projects
	5.5 Presentation and evaluation of research or development projects

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