Protein Chemistry, 6 credits

Proteinkemi, 6 hp

TFKE46

Main field of study

Biotechnology Chemical Biology Chemistry

Course level

Second cycle

Course type

Programme course

Examiner

Lars-Göran Mårtensson

Director of studies or equivalent

Magdalena Svensson

Education components

Preliminary scheduled hours: 41 h
Recommended self-study hours: 119 h

Available for exchange students

Yes
ECV = Elective / Compulsory / Voluntary
Course offered for Semester Period Timetable module Language Campus ECV
6CKEB Chemical Biology, M Sc in Engineering 6 (Spring 2019) 1 1+2 English Linköping C

Main field of study

Biotechnology, Chemical Biology, Chemistry

Course level

Second cycle

Advancement level

A1X

Course offered for

  • Chemical Biology, M Sc in Engineering

Entry requirements

Note: Admission requirements for non-programme students usually also include admission requirements for the programme and threshold requirements for progression within the programme, or corresponding.

Prerequisites

General Chemistry,Physical Chemistry, Organic Chemistry 1 and Biochemistry 1 & 2 or equivalent courses.

Intended learning outcomes

The objective of the course is to provide comprehensive knowledge in the following areas: protein chemistry, protein engineering, structure and function relationships, physicochemical properties of proteins and methodologies for characterization of proteins.
After studies well learned the student will have proficiency to:

  • Identify structure motifs and from this draw conclusions regarding the structure and function of proteins.
  • Search for information from various data bases to visualize protein structures and compare amino acid sequences.
  • Draw conclusions about protein dynamics, structure and function from detailed chemical and physical properties.
  • Comprehend the fundamental mechanisms of protein folding and to have a deeper understanding of the factors determining the stability of a protein.

Course content

Studies of different structure motifs of proteins, membrane proteins, prediction, of protein structures. Studies of physico-chemical properties of proteins and methodology for studies of these properties: Chemical characteristics of polypeptides, protein engineering, physical interactions determining the properties of proteins, role of hydrophobic interaction, conformation flexibility, protein stability, mechanisms of protein folding, interaction with other proteins, enzyme catalysis.

Teaching and working methods

The theory is presented at lectures and lessons. Three-dimensional structures of proteins and computer simulations are performed in smaller groups.

Examination

TEN5Written examination6 creditsU, 3, 4, 5

Grades

Four-grade scale, LiU, U, 3, 4, 5

Department

Institutionen för fysik, kemi och biologi

Director of Studies or equivalent

Magdalena Svensson

Examiner

Lars-Göran Mårtensson

Education components

Preliminary scheduled hours: 41 h
Recommended self-study hours: 119 h

Course literature

David Whitford: Proteins Structure and Function, Wiley.
Code Name Scope Grading scale
TEN5 Written examination 6 credits U, 3, 4, 5
David Whitford: Proteins Structure and Function, Wiley.

Note: The course matrix might contain more information in Swedish.

I = Introduce, U = Teach, A = Utilize
I U A Modules Comment
1. DISCIPLINARY KNOWLEDGE AND REASONING
1.1 Knowledge of underlying mathematics and science (G1X level)
X
TEN5

                            
1.2 Fundamental engineering knowledge (G1X level)
X
TEN5

                            
1.3 Further knowledge, methods, and tools in one or several subjects in engineering or natural science (G2X level)
X
TEN5

                            
1.4 Advanced knowledge, methods, and tools in one or several subjects in engineering or natural sciences (A1X level)

                            
1.5 Insight into current research and development work

                            
2. PERSONAL AND PROFESSIONAL SKILLS AND ATTRIBUTES
2.1 Analytical reasoning and problem solving
X
TEN5

                            
2.2 Experimentation, investigation, and knowledge discovery
X
TEN5

                            
2.3 System thinking
X
TEN5

                            
2.4 Attitudes, thought, and learning
X
TEN5

                            
2.5 Ethics, equity, and other responsibilities
X
TEN5

                            
3. INTERPERSONAL SKILLS: TEAMWORK AND COMMUNICATION
3.1 Teamwork

                            
3.2 Communications

                            
3.3 Communication in foreign languages
X
TEN5

                            
4. CONCEIVING, DESIGNING, IMPLEMENTING AND OPERATING SYSTEMS IN THE ENTERPRISE, SOCIETAL AND ENVIRONMENTAL CONTEXT
4.1 External, societal, and environmental context

                            
4.2 Enterprise and business context

                            
4.3 Conceiving, system engineering and management

                            
4.4 Designing

                            
4.5 Implementing

                            
4.6 Operating

                            
5. PLANNING, EXECUTION AND PRESENTATION OF RESEARCH DEVELOPMENT PROJECTS WITH RESPECT TO SCIENTIFIC AND SOCIETAL NEEDS AND REQUIREMENTS
5.1 Societal conditions, including economic, social, and ecological aspects of sustainable development for knowledge development

                            
5.2 Economic conditions for knowledge development

                            
5.3 Identification of needs, structuring and planning of research or development projects

                            
5.4 Execution of research or development projects

                            
5.5 Presentation and evaluation of research or development projects

                            

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