Student rights and obligations (login required)
Linköping University common rules and regulations (in Swedish)
Industrial Biotechnology, 6 credits
Industriell bioteknik, 6 hp
TFYA32
Main field of study
Engineering BiologyCourse level
Second cycleCourse type
Programme courseExaminer
Carl-Fredrik MandeniusDirector of studies or equivalent
Magnus BomanEducation components
Preliminary scheduled hours: 56 hRecommended self-study hours: 104 h
ECV = Elective / Compulsory / Voluntary
| Course offered for | Semester | Period | Timetable module | Language | Campus | ECV | |
|---|---|---|---|---|---|---|---|
| 6CKEB | Chemical Biology, M Sc in Engineering (Industrial Biotechnology and Production) | 7 (Autumn 2017) | 2 | 1 | Swedish | Linköping, Valla | C |
| 6CKEB | Chemical Biology, M Sc in Engineering (Protein Science and Technology) | 7 (Autumn 2017) | 2 | 1 | Swedish | Linköping, Valla | E |
| 6CTBI | Engineering Biology, M Sc in Engineering (Devices and Materials in Biomedicine) | 9 (Autumn 2017) | 2 | 1 | Swedish | Linköping, Valla | E |
| 6CTBI | Engineering Biology, M Sc in Engineering (Industrial biotechnology and production) | 7 (Autumn 2017) | 2 | 1 | Swedish | Linköping, Valla | C |
Main field of study
Engineering BiologyCourse level
Second cycleAdvancement level
A1XCourse offered for
- Chemical Biology, M Sc in Engineering
- Engineering Biology, M Sc in Engineering
Entry requirements
Note: Admission requirements for non-programme students usually also include admission requirements for the programme and threshold requirements for progression within the programme, or corresponding.
Prerequisites
Basic biology, chemistry and mathematics as in the TB/KB curricula of 1-3 years, or equivalentIntended learning outcomes
Fundamental understanding of industrial biotechnology with focus on products such as drugs, food, chemicals, renewable energy sources and instruments and process equipment. Understanding of metabolic and cell biological processes from engineering perspectives.
After the course the student shall be able to:
1) Describe the fundamental biological and engineering principles for production of proteins, metabolites and cells and devices and apparatuses.
2) Understand the principles for engineering design of key unit operations and other functional operations such as bioreactor cultivation and chromatographic separation of bioproducts and analytical instruments.
3) Carry out engineering computations and simulations of bioprocesses based on physical, chemical and biological fundamentals using basic mathematical equations and models.
Course content
The lectures cover fundamentals about industrial production using bioprocesses. This includes methods for cultivation in bioreactors and recovery of bioproducts using separation methods. Engineering modelling methods are used to calculate key process parameters. Content of lectures: Biochemistry and physiology of cell growth and metabolism. "The Cell Factory" concept. Bioreactor design for batch, fed-batch and chemostat. Purification and separation processes. Using dynamic models and differential equations based on balances and microbial kinetics. Design of unit operations for cultivation and bioseparation. Typical industrial bioprocesses are illuminated (e.g. production of antibiotics, biogas, industrial enzymes, therapeutic proteins, vaccines, mammalian cells, stem cells and environmental applications).
Teaching and working methods
Lectures and seminars. Simulation exercises.
Examination
| PRA1 | Written report | 1.5 credits | U, G |
| TEN2 | Written examination | 4.5 credits | U, 3, 4, 5 |
A written examination tests the student's ability to solve process engineering problems and ability to describe fundamental concepts in industrial biotechnology. Laboratory exercise reports examine the understanding of biological, physical and chemical effects and transformations using simulations and other calculation methods.
Grades
Four-grade scale, LiU, U, 3, 4, 5Other information
Supplementary courses: Biotechnical production systems, Design project for bioprocesses and production systems, Biotechnology manufacturing technique, Pharmaceutical Development, Quality management.
Department
Institutionen för fysik, kemi och biologiDirector of Studies or equivalent
Magnus BomanExaminer
Carl-Fredrik MandeniusEducation components
Preliminary scheduled hours: 56 hRecommended self-study hours: 104 h
Course literature
Mandenius CF,Industriell Bioteknik, Tryckakademin, Linköping| Code | Name | Scope | Grading scale |
|---|---|---|---|
| PRA1 | Written report | 1.5 credits | U, G |
| TEN2 | Written examination | 4.5 credits | U, 3, 4, 5 |
A written examination tests the student's ability to solve process engineering problems and ability to describe fundamental concepts in industrial biotechnology. Laboratory exercise reports examine the understanding of biological, physical and chemical effects and transformations using simulations and other calculation methods.
Regulations (apply to LiU in its entirety)
The university is a government agency whose operations are regulated by legislation and ordinances, which include the Higher Education Act and the Higher Education Ordinance. In addition to legislation and ordinances, operations are subject to several policy documents. The Linköping University rule book collects currently valid decisions of a regulatory nature taken by the university board, the vice-chancellor and faculty/department boards.
LiU’s rule book for education at first-cycle and second-cycle levels is available at http://styrdokument.liu.se/Regelsamling/Innehall/Utbildning_pa_grund-_och_avancerad_niva.
Course literature is preliminary.
Mandenius CF,Industriell Bioteknik, Tryckakademin, Linköping
Note: The course matrix might contain more information in Swedish.
I = Introduce, U = Teach, A = Utilize
| I | U | A | Modules | Comment | ||
|---|---|---|---|---|---|---|
| 1. DISCIPLINARY KNOWLEDGE AND REASONING | ||||||
| 1.1 Knowledge of underlying mathematics and science (G1X level) |
|
|
X
|
|||
| 1.2 Fundamental engineering knowledge (G1X level) |
|
|
X
|
|||
| 1.3 Further knowledge, methods, and tools in one or several subjects in engineering or natural science (G2X level) |
|
|
X
|
|||
| 1.4 Advanced knowledge, methods, and tools in one or several subjects in engineering or natural sciences (A1X level) |
|
|
|
|||
| 1.5 Insight into current research and development work |
|
|
|
|||
| 2. PERSONAL AND PROFESSIONAL SKILLS AND ATTRIBUTES | ||||||
| 2.1 Analytical reasoning and problem solving |
|
X
|
|
|||
| 2.2 Experimentation, investigation, and knowledge discovery |
|
X
|
|
PRA1
|
||
| 2.3 System thinking |
|
|
X
|
|||
| 2.4 Attitudes, thought, and learning |
|
|
X
|
PRA1
|
||
| 2.5 Ethics, equity, and other responsibilities |
|
X
|
|
|||
| 3. INTERPERSONAL SKILLS: TEAMWORK AND COMMUNICATION | ||||||
| 3.1 Teamwork |
|
X
|
|
PRA1
|
||
| 3.2 Communications |
|
|
|
|||
| 3.3 Communication in foreign languages |
|
|
|
|||
| 4. CONCEIVING, DESIGNING, IMPLEMENTING AND OPERATING SYSTEMS IN THE ENTERPRISE, SOCIETAL AND ENVIRONMENTAL CONTEXT | ||||||
| 4.1 External, societal, and environmental context |
|
|
|
|||
| 4.2 Enterprise and business context |
|
X
|
|
|||
| 4.3 Conceiving, system engineering and management |
|
X
|
|
PRA1
|
||
| 4.4 Designing |
|
X
|
|
|||
| 4.5 Implementing |
|
|
|
|||
| 4.6 Operating |
|
|
|
|||
| 5. PLANNING, EXECUTION AND PRESENTATION OF RESEARCH DEVELOPMENT PROJECTS WITH RESPECT TO SCIENTIFIC AND SOCIETAL NEEDS AND REQUIREMENTS | ||||||
| 5.1 Societal conditions, including economic, social, and ecological aspects of sustainable development for knowledge development |
|
X
|
|
|||
| 5.2 Economic conditions for knowledge development |
|
|
|
|||
| 5.3 Identification of needs, structuring and planning of research or development projects |
|
|
|
|||
| 5.4 Execution of research or development projects |
|
|
|
|||
| 5.5 Presentation and evaluation of research or development projects |
|
|
X
|
PRA1
|
||
This tab contains public material from the course room in Lisam. The information published here is not legally binding, such material can be found under the other tabs on this page.
There are no files available for this course.