Introduction to Biosensor Technology, 6 credits

Introduktion till biosensorteknik, 6 hp

TFYA62

Course starting semester

Main field of study

Applied Physics Physics Biomedical Engineering

Course level

First cycle

Course type

Programme course

Examiner

Edwin Jager

Director of studies or equivalent

Magnus Boman

Education components

Preliminary scheduled hours: 80 h
Recommended self-study hours: 80 h

Available for exchange students

Yes

Possible deviation from course syllabus/programme syllabus

ECV = Elective / Compulsory / Voluntary

Course offered for		Semester	Period	Timetable module	Language	Campus	ECV
6CMED	Biomedical Engineering, M Sc in Engineering	4 (Spring 2017)	1	4	English	Linköping, Valla	C
6CIEI	Industrial Engineering and Management - International, M Sc in Engineering	8 (Spring 2017)	1	4	English	Linköping, Valla	E
6CIEI	Industrial Engineering and Management - International, M Sc in Engineering	8 (Spring 2017)	1	4	English	Linköping, Valla	E
6CIEI	Industrial Engineering and Management - International, M Sc in Engineering	8 (Spring 2017)	1	4	English	Linköping, Valla	E
6CIEI	Industrial Engineering and Management - International, M Sc in Engineering	8 (Spring 2017)	1	4	English	Linköping, Valla	E
6CIEI	Industrial Engineering and Management - International, M Sc in Engineering	8 (Spring 2017)	1	4	English	Linköping, Valla	E
6CIII	Industrial Engineering and Management, M Sc in Engineering	8 (Spring 2017)	1	4	English	Linköping, Valla	E

Main field of study

Applied Physics, Physics, Biomedical Engineering

Course level

First cycle

Advancement level

G2X

Course offered for

Biomedical Engineering, M Sc in Engineering
Industrial Engineering and Management - International, M Sc in Engineering
Industrial Engineering and Management, M Sc in Engineering

Entry requirements

Note: Admission requirements for non-programme students usually also include admission requirements for the programme and threshold requirements for progression within the programme, or corresponding.

Prerequisites

Biochemistry and Cell Biology, Materials for Biomedical Engineering

Intended learning outcomes

The purpose of the course is to provide a broad introduction to biosensor technology including:

Working principle of the biosensors,
Biosensors classification,
Use of biological macromolecules as sensing elements,
Presenting how engineering and biology can be used to perform diagnosis.

After finishing the course the student should be able to:

Describe the working principles of biosensors,
Explain the nature and mechanism of the biorecognition event,
Describe and explain the main transduction techniques used in biosensor technology,
Evaluate a sensor based on standard performance criteria and appropriateness for a given application.

Course content

Introduction to biosensors,
Biorecognition elements,
Transduction principle,
Surface functionalization in biosensors,
Surface plasmon resonance biosensors (Biacore),
Catalytic biosensors (glucosensor),
Antibodies based biosensors,
DNA based biosensors,
Nanomaterial in biosensor technology,
Microsystem working principles and their application to biosensor technology,
Analytical parameters for sensor evaluation.

Teaching and working methods

The course includes tutorial sessions, seminars, lectures, group works and laboratory work.

Laboratory work:
Laboratory tasks/demonstrations will be held at the IFM: students will be asked to prepare, for each demonstration/exercise, a report or to answer to a questionary.
Group work
Students will be divided in teams, and each team will be assigned a research article. Each team will be asked to prepare a presentation (to be present in front of the class). Moreover each student will be asked to prepare a individual assay to demonstrate her/his understanding of the assigned article.

Examination

UPG1	Group work of exercise	2.5 credits	U, G
LAB1	Laboratory work and reports	1 credits	U, G
TEN1	Written tests	2.5 credits	U, 3, 4, 5

Grading will be based on final written test, laboratory reports and group work exercise. When all assignments are approved a final grade will be calculated as a weighted mean where the written examination gives 60% of the final mark and the group work will contribute with 40%.

Grades

Four-grade scale, LiU, U, 3, 4, 5

Department

Institutionen för fysik, kemi och biologi

Director of Studies or equivalent

Magnus Boman

Examiner

Edwin Jager

Course website and other links

http://www.ifm.liu.se/edu/coursescms/tfya62/

Education components

Preliminary scheduled hours: 80 h
Recommended self-study hours: 80 h

Course literature

Föreläsningsanteckningar, artiklar och senare bestämt litteratur Handbook of Biosensors and Biochips; Robert S. Marks, Christopher R. Lowe, David C. Cullen, Howard H. Weetall, Isao Karube, (2007) Wiley (e-book). Chemical sensors and biosensors; Brian R. Eggins (2002) Wiley (tillgänglig i biblioteket). Biosensors. The Practical Approach Series, Cooper, Jonathan M.; Cass, Anthony E. G. (2004), Volume 268 (tillgänglig i biblioteket).

Code	Name	Scope	Grading scale
UPG1	Group work of exercise	2.5 credits	U, G
LAB1	Laboratory work and reports	1 credits	U, G
TEN1	Written tests	2.5 credits	U, 3, 4, 5

Regulations (apply to LiU in its entirety)

The university is a government agency whose operations are regulated by legislation and ordinances, which include the Higher Education Act and the Higher Education Ordinance. In addition to legislation and ordinances, operations are subject to several policy documents. The Linköping University rule book collects currently valid decisions of a regulatory nature taken by the university board, the vice-chancellor and faculty/department boards.

LiU’s rule book for education at first-cycle and second-cycle levels is available at http://styrdokument.liu.se/Regelsamling/Innehall/Utbildning_pa_grund-_och_avancerad_niva.

Student rights and obligations (login required)
Linköping University common rules and regulations (in Swedish)

Course literature is preliminary.

Download

Download course literature list as PDF

Note: The course matrix might contain more information in Swedish.

I = Introduce, U = Teach, A = Utilize

		U	A
1. DISCIPLINARY KNOWLEDGE AND REASONING
	1.1 Knowledge of underlying mathematics and science (G1X level)	X
	1.2 Fundamental engineering knowledge (G1X level)	X
	1.3 Further knowledge, methods, and tools in one or several subjects in engineering or natural science (G2X level)
	1.4 Advanced knowledge, methods, and tools in one or several subjects in engineering or natural sciences (A1X level)
	1.5 Insight into current research and development work
2. PERSONAL AND PROFESSIONAL SKILLS AND ATTRIBUTES
	2.1 Analytical reasoning and problem solving
	2.2 Experimentation, investigation, and knowledge discovery
	2.3 System thinking
	2.4 Attitudes, thought, and learning
	2.5 Ethics, equity, and other responsibilities
3. INTERPERSONAL SKILLS: TEAMWORK AND COMMUNICATION
	3.1 Teamwork		X
	3.2 Communications		X
	3.3 Communication in foreign languages		X
4. CONCEIVING, DESIGNING, IMPLEMENTING AND OPERATING SYSTEMS IN THE ENTERPRISE, SOCIETAL AND ENVIRONMENTAL CONTEXT
	4.1 External, societal, and environmental context
	4.2 Enterprise and business context
	4.3 Conceiving, system engineering and management
	4.4 Designing
	4.5 Implementing
	4.6 Operating
5. PLANNING, EXECUTION AND PRESENTATION OF RESEARCH DEVELOPMENT PROJECTS WITH RESPECT TO SCIENTIFIC AND SOCIETAL NEEDS AND REQUIREMENTS
	5.1 Societal conditions, including economic, social, and ecological aspects of sustainable development for knowledge development
	5.2 Economic conditions for knowledge development
	5.3 Identification of needs, structuring and planning of research or development projects
	5.4 Execution of research or development projects
	5.5 Presentation and evaluation of research or development projects

This tab contains public material from the course room in Lisam. The information published here is not legally binding, such material can be found under the other tabs on this page.

There are no files available for this course.