Introduction to Biosensor Technology, 6 credits

Introduktion till biosensorteknik, 6 hp

TFYA62

Main field of study

Applied Physics Physics Biomedical Engineering

Course level

First cycle

Course type

Programme course

Examiner

Edwin Jager

Director of studies or equivalent

Magnus Boman

Education components

Preliminary scheduled hours: 80 h
Recommended self-study hours: 80 h

Available for exchange students

Yes
Course offered for Semester Period Timetable module Language Campus ECV
6CMED Biomedical Engineering, M Sc in Engineering 4 (Spring 2017) 1 4 English Linköping C
6CIEI Industrial Engineering and Management - International, M Sc in Engineering 8 (Spring 2017) 1 4 English Linköping E
6CIEI Industrial Engineering and Management - International, M Sc in Engineering 8 (Spring 2017) 1 4 English Linköping E
6CIEI Industrial Engineering and Management - International, M Sc in Engineering 8 (Spring 2017) 1 4 English Linköping E
6CIEI Industrial Engineering and Management - International, M Sc in Engineering 8 (Spring 2017) 1 4 English Linköping E
6CIEI Industrial Engineering and Management - International, M Sc in Engineering 8 (Spring 2017) 1 4 English Linköping E
6CIII Industrial Engineering and Management, M Sc in Engineering 8 (Spring 2017) 1 4 English Linköping E
ECV = Elective / Compulsory / Voluntary

Main field of study

Applied Physics, Physics, Biomedical Engineering

Course level

First cycle

Advancement level

G2X

Course offered for

  • Biomedical Engineering, M Sc in Engineering
  • Industrial Engineering and Management - International, M Sc in Engineering
  • Industrial Engineering and Management, M Sc in Engineering

Entry requirements

Note: Admission requirements for non-programme students usually also include admission requirements for the programme and threshold requirements for progression within the programme, or corresponding.

Prerequisites

Biochemistry and Cell Biology, Materials for Biomedical Engineering

Intended learning outcomes

The purpose of the course is to provide a broad introduction to biosensor technology including:

  • Working principle of the biosensors,
  • Biosensors classification,
  • Use of biological macromolecules as sensing elements,
  • Presenting how engineering and biology can be used to perform diagnosis.


After finishing the course the student should be able to:

  • Describe the working principles of biosensors,
  • Explain the nature and mechanism of the biorecognition event,
  • Describe and explain the main transduction techniques used in biosensor technology,
  • Evaluate a sensor based on standard performance criteria and appropriateness for a given application.

 

Course content

 

  • Introduction to biosensors,
  • Biorecognition elements,
  • Transduction principle,
  • Surface functionalization in biosensors,
  • Surface plasmon resonance biosensors (Biacore),
  • Catalytic biosensors (glucosensor),
  • Antibodies based biosensors,
  • DNA based biosensors,
  • Nanomaterial in biosensor technology,
  • Microsystem working principles and their application to biosensor technology,
  • Analytical parameters for sensor evaluation.

     

Teaching and working methods

The course includes tutorial sessions, seminars, lectures, group works and laboratory work.

Laboratory work:
Laboratory tasks/demonstrations will be held at the IFM: students will be asked to prepare, for each demonstration/exercise, a report or to answer to a questionary.
Group work
Students will be divided in teams, and each team will be assigned a research article. Each team will be asked to prepare a presentation (to be present in front of the class). Moreover each student will be asked to prepare a individual assay to demonstrate her/his understanding of the assigned article.

Examination

TEN1Written tests2.5 creditsU, 3, 4, 5
LAB1Laboratory work and reports1 creditsU, G
UPG1Group work of exercise2.5 creditsU, G

Grading will be based on final written test, laboratory reports and group work exercise. When all assignments are approved a final grade will be calculated as a weighted mean where the written examination gives 60% of the final mark and the group work will contribute with 40%.

Grades

Four-grade scale, LiU, U, 3, 4, 5

Department

Institutionen för fysik, kemi och biologi

Director of Studies or equivalent

Magnus Boman

Examiner

Edwin Jager

Course website and other links

http://www.ifm.liu.se/edu/coursescms/tfya62/

Education components

Preliminary scheduled hours: 80 h
Recommended self-study hours: 80 h

Course literature

Föreläsningsanteckningar, artiklar och senare bestämt litteratur Handbook of Biosensors and Biochips; Robert S. Marks, Christopher R. Lowe, David C. Cullen, Howard H. Weetall, Isao Karube, (2007) Wiley (e-book). Chemical sensors and biosensors; Brian R. Eggins (2002) Wiley (tillgänglig i biblioteket). Biosensors. The Practical Approach Series, Cooper, Jonathan M.; Cass, Anthony E. G. (2004), Volume 268 (tillgänglig i biblioteket).
Code Name Scope Grading scale
TEN1 Written tests 2.5 credits U, 3, 4, 5
LAB1 Laboratory work and reports 1 credits U, G
UPG1 Group work of exercise 2.5 credits U, G

Grading will be based on final written test, laboratory reports and group work exercise. When all assignments are approved a final grade will be calculated as a weighted mean where the written examination gives 60% of the final mark and the group work will contribute with 40%.

Regulations (apply to LiU in its entirety)

The university is a government agency whose operations are regulated by legislation and ordinances, which include the Higher Education Act and the Higher Education Ordinance. In addition to legislation and ordinances, operations are subject to several policy documents. The Linköping University rule book collects currently valid decisions of a regulatory nature taken by the university board, the vice-chancellor and faculty/department boards.

LiU’s rule book for education at first-cycle and second-cycle levels is available at http://styrdokument.liu.se/Regelsamling/Innehall/Utbildning_pa_grund-_och_avancerad_niva. 

Föreläsningsanteckningar, artiklar och senare bestämt litteratur Handbook of Biosensors and Biochips; Robert S. Marks, Christopher R. Lowe, David C. Cullen, Howard H. Weetall, Isao Karube, (2007) Wiley (e-book). Chemical sensors and biosensors; Brian R. Eggins (2002) Wiley (tillgänglig i biblioteket). Biosensors. The Practical Approach Series, Cooper, Jonathan M.; Cass, Anthony E. G. (2004), Volume 268 (tillgänglig i biblioteket).

Note: The course matrix is not fully translated to English.

I U A Modules Comment
1. ÄMNESKUNSKAPER
1.1 Kunskaper i grundläggande matematiska och naturvetenskapliga ämnen
X
1.2 Kunskaper i grundläggande (motsvarande G1X) teknikvetenskapliga ämnen
X
1.3 Fördjupade kunskaper (motsvarande G2X), metoder och verktyg inom något/några teknik- och naturvetenskapliga ämnen
1.4 Väsentligt fördjupade kunskaper (motsvarande A1X), metoder och verktyg inom något/några teknik- och naturvetenskapliga ämnen
1.5 Insikt i aktuellt forsknings- och utvecklingsarbete
2. INDIVIDUELLA OCH YRKESMÄSSIGA FÄRDIGHETER OCH FÖRHÅLLNINGSSÄTT
2.1 Analytiskt tänkande och problemlösning
2.2 Experimenterande och undersökande arbetssätt samt kunskapsbildning
2.3 Systemtänkande
2.4 Förhållningssätt, tänkande och lärande
2.5 Etik, likabehandling och ansvarstagande
3. FÖRMÅGA ATT ARBETA I GRUPP OCH ATT KOMMUNICERA
3.1 Arbete i grupp
X
Laborationer och mindre projektarbete i grupp.
3.2 Kommunikation
X
Laborationsrapport. Projektrapport och muntlig redovisning.
3.3 Kommunikation på främmande språk
X
Rapporter och presentationer på engelska.
4. PLANERING, UTVECKLING, REALISERING OCH DRIFT AV TEKNISKA PRODUKTER OCH SYSTEM MED HÄNSYN TILL AFFÄRSMÄSSIGA OCH SAMHÄLLELIGA BEHOV OCH KRAV
4.1 Samhälleliga villkor, inklusive ekonomiskt, socialt och ekologiskt hållbar utveckling för kunskapsutveckling
4.2 Företags- och affärsmässiga villkor
4.3 Att identifiera behov samt strukturera och planera utveckling av produkter och system
4.4 Att konstruera produkter och system
4.5 Att realisera produkter och system
4.6 Att ta i drift och använda produkter och system
5. PLANERING, GENOMFÖRANDE OCH PRESENTATION AV FORSKNINGS- ELLER UTVECKLINGSPROJEKT MED HÄNSYN TILL VETENSKAPLIGA OCH SAMHÄLLELIGA BEHOV OCH KRAV
5.1 Samhälleliga villkor, inklusive ekonomiskt, socialt och ekologiskt hållbar utveckling
5.2 Ekonomiska villkor för kunskapsutveckling
5.3 Att identifiera behov samt strukturera och planera forsknings- eller utvecklingsprojekt
5.4 Att genomföra forsknings- eller utvecklingsprojekt
5.5 Att redovisa och utvärdera forsknings- eller utvecklingsprojekt

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