Biological Measurements, 6 credits

Biomätteknik, 6 hp

TFKE37

Main field of study

Biotechnology Chemical Biology

Course level

First cycle

Course type

Programme course

Examiner

Maria Sunnerhagen

Director of studies or equivalent

Magdalena Svensson

Education components

Preliminary scheduled hours: 48 h
Recommended self-study hours: 112 h

Available for exchange students

Yes
ECV = Elective / Compulsory / Voluntary
Course offered for Semester Period Timetable module Language Campus ECV
6KKEB Chemical Biology 5 (Autumn 2017) 1 - English Linköping, Valla C
6CKEB Chemical Biology, M Sc in Engineering 5 (Autumn 2017) 1 - English Linköping, Valla C
6MPRO Protein Science, Master's Programme (External) 1 (Autumn 2017) 1 - English Linköping, Valla C

Main field of study

Biotechnology, Chemical Biology

Course level

First cycle

Advancement level

G2X

Course offered for

  • Protein Science, Master's Programme
  • Chemical Biology, M Sc in Engineering
  • Chemical Biology

Entry requirements

Note: Admission requirements for non-programme students usually also include admission requirements for the programme and threshold requirements for progression within the programme, or corresponding.

Prerequisites

Biokemi 2 (or similar), Physical Chemistry

Intended learning outcomes

The objectives of the course is to provide comprehensive knowledge in the following areas: Measurable properties of biomolecules, light spectroscopy, nuclear magnetic resonance, calorimetry, surface plasmon resonance, fundamental principles for separation based on macromolecular mobility in centrifugal- and electrical force fields as well as direct forces. Furthermore, comprehensive knowledge will be provided regarding applications of these methods within clinical and biomedical analysis, both functional and qualitative. After studies well learned the student will have proficiency to:

  • Understand and explain the theory behind the methods that are explained in the course.
  • Describe areas of application as well as advantages and limitations with the different methods.
  • Analyze, evaluate and draw conclusions from results obtained with the methods treated in the course.
  • Propose methods and strategies for studies of specific questions within biochemical and biomedical analysis, and communicate these proposals in novel contexts.
  • Investigate laboratory techniques and practice some of the methods treated in the course.

Course content

Different optical methods for the study of biological systems, such as UV, IR, FT-IR, circular dichroism (CD) and fluorescence spectroscopy, calorimetric methods, surface plasmon resonance (SPR), and the fundamental principles for separation by macromolecular mobility in centrifugal and electrical fields, such as electrophoresis, sedimentation analysis and mass spectrometry. The laboratory exercises will include practice or demonstration of a majority of the techniques treated in the lecture course.

Teaching and working methods

Lectures, seminars and laboratory exercises.

Examination

TEN1Written examination4.5 creditsU, 3, 4, 5
LAB1Laboratory work incl. oral presentation of project1.5 creditsU, G

Grades

Four-grade scale, LiU, U, 3, 4, 5

Department

Institutionen för fysik, kemi och biologi

Director of Studies or equivalent

Magdalena Svensson

Examiner

Maria Sunnerhagen

Education components

Preliminary scheduled hours: 48 h
Recommended self-study hours: 112 h

Course literature

Additional literature

Compendia


  • Compendium with extracts from reference literature, reviews, scientific articles and lab tutorials. The reference literature is mainaly extracted from: 
    Biophysical Chemistry part II. Cantor & Schimmel, Freeman NY 1980. 
    Principles of Physical Biochemistry. VanHolde, Johnsson & Ho. Prentice Hall 1998. 
    Principles and techniques of practical biochemistry. Wilson & Walker, Cambridge University Press 2000. 
    Protein-Ligand Interactions: hydrodynamics and calorimetry samt Protein-Ligand Interactions: structure and spectroscopy, Harding & Chowdry, Oxford University Press 2001.
Code Name Scope Grading scale
TEN1 Written examination 4.5 credits U, 3, 4, 5
LAB1 Laboratory work incl. oral presentation of project 1.5 credits U, G

Regulations (apply to LiU in its entirety)

The university is a government agency whose operations are regulated by legislation and ordinances, which include the Higher Education Act and the Higher Education Ordinance. In addition to legislation and ordinances, operations are subject to several policy documents. The Linköping University rule book collects currently valid decisions of a regulatory nature taken by the university board, the vice-chancellor and faculty/department boards.

LiU’s rule book for education at first-cycle and second-cycle levels is available at http://styrdokument.liu.se/Regelsamling/Innehall/Utbildning_pa_grund-_och_avancerad_niva. 

Additional literature

Compendia

Compendium with extracts from reference literature, reviews, scientific articles and lab tutorials. The reference literature is mainaly extracted from: 
Biophysical Chemistry part II. Cantor & Schimmel, Freeman NY 1980. 
Principles of Physical Biochemistry. VanHolde, Johnsson & Ho. Prentice Hall 1998. 
Principles and techniques of practical biochemistry. Wilson & Walker, Cambridge University Press 2000. 
Protein-Ligand Interactions: hydrodynamics and calorimetry samt Protein-Ligand Interactions: structure and spectroscopy, Harding & Chowdry, Oxford University Press 2001.

Note: The course matrix might contain more information in Swedish.

I = Introduce, U = Teach, A = Utilize
I U A Modules Comment
1. DISCIPLINARY KNOWLEDGE AND REASONING
1.1 Knowledge of underlying mathematics and science (G1X level)
X
X
TEN1

                            
1.2 Fundamental engineering knowledge (G1X level)
X
X
LAB1
TEN1

                            
1.3 Further knowledge, methods, and tools in one or several subjects in engineering or natural science (G2X level)
X
LAB1
TEN1

                            
1.4 Advanced knowledge, methods, and tools in one or several subjects in engineering or natural sciences (A1X level)

                            
1.5 Insight into current research and development work

                            
2. PERSONAL AND PROFESSIONAL SKILLS AND ATTRIBUTES
2.1 Analytical reasoning and problem solving
X
X
LAB1
TEN1

                            
2.2 Experimentation, investigation, and knowledge discovery
X
X
LAB1

                            
2.3 System thinking

                            
2.4 Attitudes, thought, and learning
X

                            
2.5 Ethics, equity, and other responsibilities
X
X
LAB1

                            
3. INTERPERSONAL SKILLS: TEAMWORK AND COMMUNICATION
3.1 Teamwork
X

                            
3.2 Communications
X

                            
3.3 Communication in foreign languages
X

                            
4. CONCEIVING, DESIGNING, IMPLEMENTING AND OPERATING SYSTEMS IN THE ENTERPRISE, SOCIETAL AND ENVIRONMENTAL CONTEXT
4.1 External, societal, and environmental context

                            
4.2 Enterprise and business context

                            
4.3 Conceiving, system engineering and management

                            
4.4 Designing

                            
4.5 Implementing

                            
4.6 Operating

                            
5. PLANNING, EXECUTION AND PRESENTATION OF RESEARCH DEVELOPMENT PROJECTS WITH RESPECT TO SCIENTIFIC AND SOCIETAL NEEDS AND REQUIREMENTS
5.1 Societal conditions, including economic, social, and ecological aspects of sustainable development for knowledge development

                            
5.2 Economic conditions for knowledge development

                            
5.3 Identification of needs, structuring and planning of research or development projects

                            
5.4 Execution of research or development projects

                            
5.5 Presentation and evaluation of research or development projects

                            

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