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Gene Technology and Molecular Genetics, 6 credits
Genteknik och molekylärgenetik, 6 hp
TVCB02
Main field of study
Biotechnology Engineering BiologyCourse level
First cycleCourse type
Programme courseExaminer
Peter SöderkvistDirector of studies or equivalent
Kajsa Holmgren PetersonEducation components
Preliminary scheduled hours: 52 hRecommended self-study hours: 108 h
ECV = Elective / Compulsory / Voluntary
| Course offered for | Semester | Period | Timetable module | Language | Campus | ECV | |
|---|---|---|---|---|---|---|---|
| 6CTBI | Engineering Biology, M Sc in Engineering | 5 (Autumn 2017) | 2 | 1+2 | Swedish | Linköping, Valla | C |
Main field of study
Biotechnology, Engineering BiologyCourse level
First cycleAdvancement level
G2XCourse offered for
- Engineering Biology, M Sc in Engineering
Entry requirements
Note: Admission requirements for non-programme students usually also include admission requirements for the programme and threshold requirements for progression within the programme, or corresponding.
Prerequisites
Biochemistry and Cell BiologyIntended learning outcomes
The course intends to provide theoretical knowledge in basic genetics and molecular genetic mechanisms. Furthermore, the course should illuminate theoretical and practical knowledge in gene technology and its application in biomedicine. By the end of the course the student will be able to:
- Integrate knowledge on how genetic information is inherited, expressed and regulated.
- Understand and explain how genetic variation originates, and affects traits and development of disease in individuals.
- Understand the theoretical background as well as perform and analyse the results of basic molecular genetic methods.
- Understand the theoretical background of more advanced gene technologies for analysis of expression and variation in the genome, mapping and cloning of genes.
- Identify relevant analytical methods for application on a specific biomedical problem.
- Independently identify a genetic topic, as a foundation for searching scientific information, which will be structured, evaluated and presented in written and oral form.
Course content
- Genetic and molecular genetic principles for inheritance, meiosis, mitosis, recombination and linkage analysis.
- Mutations, polymorphisms, DNA repair and control of gene expression in eukaryotic cells.
- Medical genetics and application of gene technologies within biomedicine, disease diagnostics, prenatal diagnostics and genetic counselling as well as applications in forensic science.
- Basic gene technologies: restriction enzymes and RFLP, separation, labelling and hybridisation of nucleic acids, PCR-based techniques and DNA sequencing. Utilising of bioinformatic tools and databases for molecular genetic studies.
- Advanced gene technologies: mutation- and expression analysis, isolation and mapping of genes, animal models for functional studies, cytogenetics.
Teaching and working methods
The course consists of lectures, seminars and laboratory work.
Examination
| UPG1 | Exercise | 1.5 credits | U, G |
| LAB1 | Laboratory Work | 1.5 credits | U, G |
| TEN1 | Examination | 3 credits | U, 3, 4, 5 |
Grades
Four-grade scale, LiU, U, 3, 4, 5Other information
Supplementery courses: Genome Analysis.
Department
Institutionen för klinisk och experimentell medicinDirector of Studies or equivalent
Kajsa Holmgren PetersonExaminer
Peter SöderkvistEducation components
Preliminary scheduled hours: 52 hRecommended self-study hours: 108 h
Course literature
Additional literature
Books
- Alberts B. et al, (2002) Molecular Biology of the Cell 4th ed
- Hyde David, Introduction to Genetic Principles
ISBN: 978-0-07-110675-7
| Code | Name | Scope | Grading scale |
|---|---|---|---|
| UPG1 | Exercise | 1.5 credits | U, G |
| LAB1 | Laboratory Work | 1.5 credits | U, G |
| TEN1 | Examination | 3 credits | U, 3, 4, 5 |
Regulations (apply to LiU in its entirety)
The university is a government agency whose operations are regulated by legislation and ordinances, which include the Higher Education Act and the Higher Education Ordinance. In addition to legislation and ordinances, operations are subject to several policy documents. The Linköping University rule book collects currently valid decisions of a regulatory nature taken by the university board, the vice-chancellor and faculty/department boards.
LiU’s rule book for education at first-cycle and second-cycle levels is available at http://styrdokument.liu.se/Regelsamling/Innehall/Utbildning_pa_grund-_och_avancerad_niva.
Course literature is preliminary.
Additional literature
Books
Alberts B. et al, (2002) Molecular Biology of the Cell 4th ed
Hyde David, Introduction to Genetic Principles
ISBN: 978-0-07-110675-7
Note: The course matrix might contain more information in Swedish.
I = Introduce, U = Teach, A = Utilize
| I | U | A | Modules | Comment | ||
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| 1. DISCIPLINARY KNOWLEDGE AND REASONING | ||||||
| 1.1 Knowledge of underlying mathematics and science (G1X level) |
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| 1.2 Fundamental engineering knowledge (G1X level) |
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| 1.3 Further knowledge, methods, and tools in one or several subjects in engineering or natural science (G2X level) |
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| 1.4 Advanced knowledge, methods, and tools in one or several subjects in engineering or natural sciences (A1X level) |
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| 1.5 Insight into current research and development work |
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| 2. PERSONAL AND PROFESSIONAL SKILLS AND ATTRIBUTES | ||||||
| 2.1 Analytical reasoning and problem solving |
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| 2.2 Experimentation, investigation, and knowledge discovery |
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| 2.3 System thinking |
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| 2.4 Attitudes, thought, and learning |
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| 2.5 Ethics, equity, and other responsibilities |
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| 3. INTERPERSONAL SKILLS: TEAMWORK AND COMMUNICATION | ||||||
| 3.1 Teamwork |
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| 3.2 Communications |
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| 3.3 Communication in foreign languages |
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| 4. CONCEIVING, DESIGNING, IMPLEMENTING AND OPERATING SYSTEMS IN THE ENTERPRISE, SOCIETAL AND ENVIRONMENTAL CONTEXT | ||||||
| 4.1 External, societal, and environmental context |
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| 4.2 Enterprise and business context |
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| 4.3 Conceiving, system engineering and management |
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| 4.4 Designing |
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| 4.5 Implementing |
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| 4.6 Operating |
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| 5. PLANNING, EXECUTION AND PRESENTATION OF RESEARCH DEVELOPMENT PROJECTS WITH RESPECT TO SCIENTIFIC AND SOCIETAL NEEDS AND REQUIREMENTS | ||||||
| 5.1 Societal conditions, including economic, social, and ecological aspects of sustainable development for knowledge development |
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| 5.2 Economic conditions for knowledge development |
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| 5.3 Identification of needs, structuring and planning of research or development projects |
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| 5.4 Execution of research or development projects |
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| 5.5 Presentation and evaluation of research or development projects |
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