Biochemistry 2, 6 credits

Biokemi 2, 6 hp

TFKE36

Course starting semester

Main field of study

Biotechnology Chemical Biology Chemistry

Course level

First cycle

Course type

Programme course

Examiner

Magdalena Svensson

Director of studies or equivalent

Magdalena Svensson

Education components

Preliminary scheduled hours: 46 h
Recommended self-study hours: 114 h

Possible deviation from course syllabus/programme syllabus

ECV = Elective / Compulsory / Voluntary

Course offered for		Semester	Period	Timetable module	Language	Campus	ECV
6KBIO	Biology	4 (Spring 2017)	2	1+4	Swedish	Linköping, Valla	E
6IKEA	Chemical Analysis Engineering, B Sc in Engineering	4 (Spring 2017)	2	1+4	Swedish	Linköping, Valla	E
6KKEB	Chemical Biology	4 (Spring 2017)	2	1+4	Swedish	Linköping, Valla	C
6CKEB	Chemical Biology, M Sc in Engineering	4 (Spring 2017)	2	1+4	Swedish	Linköping, Valla	C
6KKEM	Chemistry	4 (Spring 2017)	2	1+4	Swedish	Linköping, Valla	C
6CTBI	Engineering Biology, M Sc in Engineering	4 (Spring 2017)	2	1+2	Swedish	Linköping, Valla	C

Main field of study

Biotechnology, Chemical Biology, Chemistry

Course level

First cycle

Advancement level

G2X

Course offered for

Chemical Biology, M Sc in Engineering
Engineering Biology, M Sc in Engineering
Chemical Analysis Engineering, B Sc in Engineering
Biology
Chemical Biology
Chemistry

Entry requirements

Note: Admission requirements for non-programme students usually also include admission requirements for the programme and threshold requirements for progression within the programme, or corresponding.

Prerequisites

General chemistry, Organic chemsitry 1 and Biochemistry 1

Intended learning outcomes

The objective of the couse is to give comprehensive knowledge within the following areas: Enzyme kinetics, enzyme mechanisms and methodology for characterization of enzymes.After studies well learned the student will have proficiency to:

Calculate kinetic parameters like kcat, KM, Vmax and KI.
Interprete the meaning of kinetic parameters in terms of enzyme function.
Recapitulate the reaction mechanism for some enzymes.
Explore fundamental laboratory techniques and interprete the obtained data in a written report.

Course content

Theory: Structure and function of enzymes. Protein folding, enzyme kinetics with different types of inhibitions. Factors causing enzyme catalysis, characterization of the active site, examples of the reation mechansims of certain enzymes. Laborations: Purification of a protein with ionic change chromatography. Functional analysis of enzymes: Enzyme activity measurement, pH-dependance, chromatogram, kinetic- and spectrophotometric studies.

Teaching and working methods

The theory is mainly presented in lectures. Solving of problems, discussions of theoretical and practical aspects of experiments in the laboratory are performed in lessons. Theoretical and practical aspects of biochemistry are illustrated in the laboratory course. The results of the experimental work should be presented and discussed in written reports.

Examination

LAB1	Laboratory work	2 credits	U, G
TEN1	Written examination	4 credits	U, 3, 4, 5

The exercises of the written examination and the test elucidate how well the student perform the demands of the course.

Grades

Four-grade scale, LiU, U, 3, 4, 5

Other information

Supplementary courses: Protein Chemistry

Department

Institutionen för fysik, kemi och biologi

Director of Studies or equivalent

Magdalena Svensson

Examiner

Magdalena Svensson

Education components

Preliminary scheduled hours: 46 h
Recommended self-study hours: 114 h

Code	Name	Scope	Grading scale
LAB1	Laboratory work	2 credits	U, G
TEN1	Written examination	4 credits	U, 3, 4, 5

The exercises of the written examination and the test elucidate how well the student perform the demands of the course.

Regulations (apply to LiU in its entirety)

The university is a government agency whose operations are regulated by legislation and ordinances, which include the Higher Education Act and the Higher Education Ordinance. In addition to legislation and ordinances, operations are subject to several policy documents. The Linköping University rule book collects currently valid decisions of a regulatory nature taken by the university board, the vice-chancellor and faculty/department boards.

LiU’s rule book for education at first-cycle and second-cycle levels is available at http://styrdokument.liu.se/Regelsamling/Innehall/Utbildning_pa_grund-_och_avancerad_niva.

Student rights and obligations (login required)
Linköping University common rules and regulations (in Swedish)

Course literature is preliminary.

There is no course literature available for this course in studieinfo.

Note: The course matrix might contain more information in Swedish.

I = Introduce, U = Teach, A = Utilize

		I	U	A
1. DISCIPLINARY KNOWLEDGE AND REASONING
	1.1 Knowledge of underlying mathematics and science (G1X level)		X	X
	1.2 Fundamental engineering knowledge (G1X level)		X	X
	1.3 Further knowledge, methods, and tools in one or several subjects in engineering or natural science (G2X level)		X
	1.4 Advanced knowledge, methods, and tools in one or several subjects in engineering or natural sciences (A1X level)
	1.5 Insight into current research and development work
2. PERSONAL AND PROFESSIONAL SKILLS AND ATTRIBUTES
	2.1 Analytical reasoning and problem solving		X	X
	2.2 Experimentation, investigation, and knowledge discovery		X
	2.3 System thinking
	2.4 Attitudes, thought, and learning
	2.5 Ethics, equity, and other responsibilities
3. INTERPERSONAL SKILLS: TEAMWORK AND COMMUNICATION
	3.1 Teamwork			X
	3.2 Communications			X
	3.3 Communication in foreign languages			X
4. CONCEIVING, DESIGNING, IMPLEMENTING AND OPERATING SYSTEMS IN THE ENTERPRISE, SOCIETAL AND ENVIRONMENTAL CONTEXT
	4.1 External, societal, and environmental context	X
	4.2 Enterprise and business context
	4.3 Conceiving, system engineering and management
	4.4 Designing
	4.5 Implementing
	4.6 Operating
5. PLANNING, EXECUTION AND PRESENTATION OF RESEARCH DEVELOPMENT PROJECTS WITH RESPECT TO SCIENTIFIC AND SOCIETAL NEEDS AND REQUIREMENTS
	5.1 Societal conditions, including economic, social, and ecological aspects of sustainable development for knowledge development
	5.2 Economic conditions for knowledge development
	5.3 Identification of needs, structuring and planning of research or development projects
	5.4 Execution of research or development projects
	5.5 Presentation and evaluation of research or development projects

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